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gmuE [2019-04-22 18:39:38]
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gmuE [2019-04-22 18:39:38]

mannose kinase
Locus
BSU05860
Isoelectric point
5.01
Molecular weight
32.29 kDa
Protein length
299 aa Sequence Blast
Gene length
900 bp Sequence Blast
Function
glucomannan utilization
Product
mannose kinase
Essential
no
E.C.
2.7.1.4
Synonyms
ydhR
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of glucomannan

    • Gene

    Coordinates
    630,912 → 631,811

    The protein

    Catalyzed reaction/ biological activity

  • ATP + mannose = ADP + mannose 6-phosphate

    • Protein family

  • ROK (nagC/xylR) family (according to Swiss-Prot)

    • Structure

  • 1XC3 PubMed

    • Expression and Regulation

    Operons

    Genes
    gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • GmuR: repression, PubMed, in GmuR regulon
  • CcpA: repression, PubMed, in CcpA regulon
  • AbrB: activation, PubMed, in AbrB regulon

    • Regulation

  • induced by cellobiose (GmuR) PubMed
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    Biological materials

    Mutant

  • MGNA-C193 (ydhR::erm), available at the NBRP B. subtilis, Japan
  • BKE05860 (ΔgmuE::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGCAGATGGCCTCCTTGT, downstream forward: _UP4_GCAGCATCCGGGGAGGTGCG
  • BKK05860 (ΔgmuE::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGCAGATGGCCTCCTTGT, downstream forward: _UP4_GCAGCATCCGGGGAGGTGCG

    • References

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